A peroxidase (eg. EC 1.11.1.9) is an enzyme, which may contain heme, that catalyzes a reaction of the form:
ROOR' + electron donor (2 e-) + 2H+ → ROH + R'OH
For many of these enzymes the optimal substrate is hydrogen peroxide, but others are more active with organic hydroperoxides such as lipid peroxides.
The nature of the electron donor is very dependent on the structure of the enzyme. For example, horseradish peroxidase can use a variety of organic compounds as electron donors and acceptors. Horseradish peroxidase has a broad and accessible active site and many compounds can reach the site of the reaction. For an enzyme such as cytochrome c peroxidase, the compounds that donate electrons are very specific, because there is a very closed active site.
Peroxidases are sometimes used as histological markers. Cytochrome c peroxidase is used as a soluble, easily purified model for cytochrome c oxidase.
Glutathione peroxidase is a peroxidase found in humans, which contains selenocysteine. It uses glutathione as an electron donor and is active with both hydrogen peroxide and organic hydroperoxide substrates.
Amyloid beta, when bound to heme has been shown to have peroxidase
Comments
It kills microbes, just like the stuff on your bathroom shelf. It produces highly reactive forms of oxygen that kill.
A peroxidase (eg. EC 1.11.1.9) is an enzyme, which may contain heme, that catalyzes a reaction of the form:
ROOR' + electron donor (2 e-) + 2H+ → ROH + R'OH
For many of these enzymes the optimal substrate is hydrogen peroxide, but others are more active with organic hydroperoxides such as lipid peroxides.
The nature of the electron donor is very dependent on the structure of the enzyme. For example, horseradish peroxidase can use a variety of organic compounds as electron donors and acceptors. Horseradish peroxidase has a broad and accessible active site and many compounds can reach the site of the reaction. For an enzyme such as cytochrome c peroxidase, the compounds that donate electrons are very specific, because there is a very closed active site.
Peroxidases are sometimes used as histological markers. Cytochrome c peroxidase is used as a soluble, easily purified model for cytochrome c oxidase.
Glutathione peroxidase is a peroxidase found in humans, which contains selenocysteine. It uses glutathione as an electron donor and is active with both hydrogen peroxide and organic hydroperoxide substrates.
Amyloid beta, when bound to heme has been shown to have peroxidase
What Is Peroxidase
It is an enzyme and thus speeds up a chemical reaction. That is the generality; you come up with the specifics in this reaction.
http://en.wikipedia.org/wiki/Peroxidase
Hi, have you done the paper could you possibly tell me what questions will come up as I need to do well in this isa and its my last chance